Facebook-f Instagram
Facebook-f Instagram
Home - Cannexus

WELCOME TO CANNEXUS, WHERE CARE MEETS CANNABIS

Cannexus is redefining the way South Africa accesses medical cannabis. With our unified legal framework, we offer patients safe, compliant, and convenient solutions to receive prescriptions. We also empower retailers with a zero‑onboarding, growth‑ready hub.

Legal & trusted access

% 10–15% member savings

Community & growth

Join Health Club
For Hubs
For Patients

Welcome to Cannexus – The Future of Medical Cannabis Access

Cannexus is redefining the way South Africa accesses medical cannabis. With our unified legal framework, we offer patients safe, compliant, and convenient solutions to receive prescriptions. At the same time, we empower retailers through innovation and growth strategies to ensure compliance while building sustainable businesses.

Cannexus Promise

• Patient-first solutions: Prioritizing safety and accessibility.
• Retailer empowerment: Providing tools for compliance and growth.
• A unified network: Connecting communities nationwide.

Cannexus Promise
Patient-first solutions: Prioritizing safety and accessibility.
Retailer empowerment: Providing tools for compliance and growth.
A unified network: Connecting communities nationwide.

Contact Us
Login

Which Diseases Can Medical Cannabis Help With?

Migraine

Problem:

Migraines cause severe headaches, nausea, and sensitivity to light and sound, often disrupting daily life. Many treatments have side effects or limited effectiveness.

Cannabis Benefits:

Cannabis helps by reducing pain, easing nausea, and lowering inflammation. THC and CBD interact with the body's pain receptors, providing relief. Indica strains and CBD-rich products can relax muscles and prevent migraine triggers. Many patients report fewer attacks and improved quality of life with medical cannabis.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

Migraine
CHRONIC PAIN CROPPED

Chronic Pain

Problem:

Chronic pain affects daily activities, causing discomfort, reduced mobility, and reliance on painkillers that may have harmful side effects. Conditions like arthritis, fibromyalgia, and nerve damage often lead to persistent pain.

Cannabis Benefits:

Cannabis offers natural pain relief by interacting with the body's endocannabinoid system. THC reduces pain perception, while CBD decreases inflammation and muscle tension. Many patients find cannabis more effective and safer than opioids, improving sleep and overall well-being.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

Chronic Pain

ADHD

Problem:

ADHD (Attention Deficit Hyperactivity Disorder) makes it hard to focus, stay organized, and control impulses. Many struggle with restlessness, anxiety, and disrupted sleep. Medications can have side effects like insomnia and loss of appetite.

Cannabis Benefits:

Cannabis, especially CBD-rich strains, promotes relaxation, improves focus, and reduces hyperactivity. It helps balance dopamine levels, which are often irregular in ADHD patients. Many report better concentration, reduced anxiety, and improved sleep without the harsh side effects of traditional medications.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

ADHD

Depression

Problem:

Depression causes persistent sadness, low energy, and loss of interest in daily life. It can affect sleep, appetite, and motivation, making even simple tasks feel overwhelming. Traditional antidepressants may take weeks to work and can have unwanted side effects.

Cannabis Benefits:

Cannabis can boost mood by stimulating dopamine and serotonin production. THC provides an uplifting effect, while CBD helps reduce stress and anxiety. Certain strains promote relaxation and motivation, helping users regain a sense of well-being and enjoyment in life.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

Depression

Obsessive-Compulsive Disorders

Problem:

Obsessive-Compulsive Disorder (OCD) causes intrusive thoughts and repetitive behaviors that can interfere with daily life. It often leads to anxiety,stress, and difficulty controlling compulsions. Medications may help but can have side effects like drowsiness and agitation.

Cannabis Benefits:

Cannabis helps regulate the brain’s stress response, reducing anxiety and obsessive thoughts. CBD is especially effective in calming compulsive behaviours, while THC can promote relaxation. Many patients experience relief from intrusive thoughts and improved emotional balance with medical cannabis.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

OCD

Osteoarthritis

Problem:

Osteoarthritis causes joint pain, stiffness, and inflammation, making movement difficult. It worsens over time and can severely impact mobility and quality of life. Pain medications may provide temporary relief but can lead to long-term side effects.

Cannabis Benefits:

Cannabis reduces inflammation and pain by interacting with the body's endocannabinoid system. CBD helps decrease swelling and stiffness, while THC provides pain relief and improves mobility. Many patients find cannabis helpful for managing symptoms without the risks of traditional painkillers.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

Osteoarthritis

Endometriosis Therapy

Problem:

Endometriosis causes severe pelvic pain, cramps, and inflammation due to tissue growing outside the uterus. It can lead to painful periods, digestive issues, and fertility problems. Traditional treatments like painkillers and hormone therapy may not work for everyone and can have side effects.

Cannabis Benefits:

Cannabis helps by reducing inflammation, easing cramps, and managing chronic pain. THC provides relief from severe discomfort, while CBD relaxes muscles and lowers inflammation. Many women find cannabis improves their quality of life by offering a natural and effective way to manage symptoms.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

Endometriosis
10

Cancer

Problem:

Cancer and its treatments, such as chemotherapy, cause severe pain, nausea, loss of appetite, and fatigue. Many patients struggle with side effects that impact their quality of life and overall well-being.

Cannabis Benefits:

Cannabis helps manage cancer-related pain, reduces nausea, and stimulates appetite. THC is effective for pain relief and increasing appetite, while CBD helps with inflammation and anxiety. Many cancer patients use cannabis to ease treatment side effects, improve sleep, and enhance their overall comfort.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

Cancer
NEUROLOGICAL-CONDITIONS-2-CROPPED

Other Conditions

Problems & Benefits:

Anxiety & Stress – CBD calms the nervous system, reducing excessive worry and promoting relaxation without sedation.

Epilepsy & Seizures – CBD has been proven to reduce seizure frequency and severity, especially in drug-resistant epilepsy.

Multiple Sclerosis (MS) – Cannabis eases muscle spasms, nerve pain, and inflammation, improving mobility and quality of life.

Irritable Bowel Syndrome (IBS) & Crohn’s Disease – CBD reduces gut inflammation and pain, improving digestion and symptom control.

Parkinson’s Disease – Cannabis helps reduce tremors, stiffness, and muscle spasms while improving sleep and mood.

Glaucoma – THC lowers intraocular pressure, which can help slow vision loss.

Fibromyalgia – Cannabis provides relief from widespread pain, fatigue, and sleep disturbances.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

Other Conditions
12

Insomnia

Problem:

Insomnia makes it difficult to fall or stay asleep, leading to fatigue, irritability, and poor concentration. It can be caused by stress, anxiety, chronic pain, or other health conditions. Many sleep medications have side effects like grogginess and dependency.

Cannabis Benefits:

Cannabis helps regulate sleep cycles by promoting relaxation and reducing anxiety. THC aids in falling asleep faster, while CBD calms the mind and prevents nighttime restlessness. Many users experience deeper, more restful sleep without the hangover effect of traditional sleep aids.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

Insomnia
23

Post-Traumatic Stress Disorder

Problem:

Post-Traumatic Stress Disorder (PTSD) causes intense anxiety, flashbacks, nightmares, and emotional numbness, often followingtraumatic events. It can lead to sleep disturbances, irritability, and difficulty functioning in daily life. Conventional treatments maynot always be effective and can have side effects.

Cannabis Benefits:

Cannabis helps manage PTSD symptoms by reducing anxiety, promoting relaxation, and improving sleep. THC can alleviate distressing flashbacks and nightmares, while CBD helps calm the nervous system and reduces emotional triggers. Many patients find cannabis a useful tool in regaining emotional balance and improving quality of life.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

PTSD
24

AIDS/HIV

Problem:

HIV/AIDS causes a weakened immune system, leading to symptoms like chronic fatigue, weight loss, pain, and nausea. Antiretroviraltreatments can have side effects, and managing symptoms often requires additional support.

Cannabis Benefits:

Cannabis helps manage pain, reduce inflammation, and alleviate nausea and loss of appetite, common in HIV/AIDS patients. THC stimulates appetite, helping combat weight loss, while CBD supports the immune system and reduces anxiety. Many find cannabis improves their quality of life and helps manage side effects from treatment.

"Please always consult with your doctor before using cannabis for medical purposes. If you’re interested in exploring how cannabis can help with your condition, make an appointment now with our doctor to discuss your options and determine the best treatment for your needs."

BOOK APPOINTMENT

Aids/HIV

What is Medical Cannabis?

Medical cannabis refers to the use of cannabis and its natural compounds, known as cannabinoids, to manage various health conditions. It is prescribed by a doctor and used in a controlled, regulated manner to provide relief from symptoms such as pain, anxiety, inflammation, and sleep disorders. Unlike recreational cannabis, medical cannabis is tailored to individual patient needs, ensuring safe and effective treatment.

Get your Section 21 for just R370!

Your chosen Cannexus Hub partner pays the other half.

After your Section 21 registration, optionally activate your Health Membership for extra discounts.

  • Script valid for 6 months
  • Register as a patient and shop with confidence
  • Stores: Join the Cannexus Hub with 0% onboarding fees and no monthly charges
→ Go to cannexuspatient.co.za

Payflex setup (optional)

  1. Go to www.payflex.co.za
  2. Register yourself there
  3. Choose your plan
  4. You are ready to go

Scan in Cannexus Hub Partner stores

Quick login

Account login or creation is required prior to registration.

Log in

Create an account

HEALTH CLUB MEMBERSHIP

Prerequisite: Valid Section 21 prescription (you pay R370, partner store covers the other half).
Then choose Health Club for member discounts.

HEALTH MEMBERSHIP

R49.99 per month

Available to Section 21 prescription patients

  • 10–15% discount on all products across all partner stores
  • Up to 15% discount on new or seasonal products
  • Hybrid Medical + Loyalty card (patient ID + loyalty)
  • Early access + product notifications
→ UPGRADE FROM PATIENT PORTAL

HUB STORES

0% onboarding fee. 0% monthly fee.
A complete compliance + growth framework.

WHAT YOU GET

  • Guided to SAHPRA-aligned best practice
  • Compliance & SOP Pack (SAHPRA-guided)
  • Training modules & certification for owners and staff
  • Approved GMP product catalogue access
  • Collection-point toolkit (door sticker, QR posters)
  • Onboard & video training (docs to run the business)
  • Marketing tools + staff tests
  • Health Membership card for discounts
  • Over 50+ strains with many more GMP‑approved products

Hub back-office login provides training, documents, and order management.

ORDERING & OPERATIONS

Centralised, transparent, compliant

  • Order all Section 21 products via the Cannexus main portal
  • Invoices generated to Cannexus, orders assembled with GMP+ prescriptions
  • Over 50+ strains on portal

At checkout we inform you that orders are assembled in line with GMP and prescription verification – this may take a few days.

Go to cannexushub.co.za
Request onboarding

ROADMAPS

Step-by-step guides for Patients and HUBS.

PATIENT ROADMAP

From signup to savings

  • Sign up via Patient Portal or in-store
  • Obtain Section 21 prescription (you pay R370; partner store covers the other half)
  • Activate Health Membership (R49.99/mo) to unlock 10–15% discount
  • Enjoy 10–15% discount across all HUB partners
View full patient roadmap

HUB STORE ROADMAP

From onboarding to ordering

  • Sign NDA & Cannexus Contract
  • Acknowledge POPI Act & Website Agreement
  • Complete staff training+ daily structure (SAHPRA-aligned)
  • Start ordering GMP products via portal
View full HUB roadmap

Our HUB Partners

Ready to Take the Next Step?

Become Part Of The

Cannexus Community

Our Franchise Stores and HUB Partners operate under the trusted Cannexus legal framework, ensuring that patients can use their Section 21 medical approvals at multiple certified locations. Whether you’re a patient seeking relief or a dispensary ready to serve your community legally, we’re here to guide you. Join us in building South Africa’s leading patient-first cannabis network where compliance meets convenience and care.

REgister Today

FAQ'S

A “Section 21 prescription” is a doctor’s prescription paired with a SAHPRA Section 21 authorisation that lets a named patient legally access an unregistered medicine in South Africa (e.g., certain medical-cannabis products). Without the SAHPRA authorisation, the prescription alone can’t be filled.

R700 total, split 50/50: you pay R370 and your Hub pays R370.

No. You can purchase as a patient with a valid Section 21 prescription/authorisation from your doctor. Health Club is optional—joining gives you extra savings and member perks, but it isn’t required to shop.

At Cannexus Hub partner stores in our network. Bring your ID and Section 21 script/authorisation. See Our HUB Partners on this page for locations.

At Cannexus Hub partner stores in our network. Bring your ID and Section 21 script/authorisation. See Our HUB Partners on this page for locations.

Section 21 approvals are time-limited (commonly up to 6 months) and don’t auto-renew. Before it expires, book a follow-up with your treating doctor. If treatment should continue, your doctor submits a new Section 21 application with updated product/dose/duration.

Yes. Cannexus follows POPIA-aligned practices: we collect only what’s needed, store it securely, and never sell your data.

Yes—any time in your account settings. Your membership stays active until the end of the current billing period and then stops. Cancelling doesn’t affect your patient profile or any valid Section 21 authorisation.

Yes—patients first create an account/login, then proceed through guided steps. This keeps documents secure and statuses clear.

Hubs apply via the Hub Login. Approved partners receive operational guidelines and compliance tooling.

Only 18+ Years & Older.

Shopping Cart
Chat with us
Need Assistance?
Scroll to Top